简历:
学习经历
1996/9-2000/7,威人斯尼登录网,学士
2002/9-2005/7,威人斯尼登录网,硕士,导师:余孝其
2006/9-2010/12,威人斯尼登录网,在职博士,导师:余孝其
工作经历
2005/7-2007/7,威人斯尼登录网,助教
2007/7-2015/9,威人斯尼登录网,讲师
2015/9-至今,威人斯尼登录网,副教授
2013/11-2014/11,美国弗吉尼亚大学,访问学者,师从蒲林教授
主要研究方向
绿色合成方法学:集中于利用简单金属盐做催化剂来构建碳-碳,碳-杂原子键。
荧光探针:构建新型荧光分子,用于生物体内成像
主要工作业绩
在有机合成方面,发展了简单钴、铜、铁金属盐催化碳氢的直接官能团化反应,并将其用于重要杂环化合物的合成,2篇论文入选高被引论文。研究成果“简单金属盐催化的C-C和C-N键形成反应” 在2011年获得获教育部自然科学一等奖(排名第四)。在荧光探针方面, 利用新的方法构建荧光分子,简化了合成路径,易于分离,并将这些荧光探针分子用生物体内一些活性物质或生命活动的追踪。
代表性成果 (获奖成果、专著、论文、专利)
1. Chen, S.-Y.; Li Z.; Li, K. *; Yu, X. Q. *, Small molecular fluorescent probes for the detection of lead, cadmium and mercury ions, Coord. Chem. Rev.2021, 429, 213619. DOI: 10.1016/j.ccr.2020.213691.
2. Yu, K. K.; Pan, S.-L.; Li, K.; Shi, L.; Liu, Y.-H.; Chen, S.-Y.*; Yu, X.-Q. *, A novel near-infrared fluorescent sensor for zero background nitrite detection via the "covalent-assembly" principle, Food Chem., 2021, 341, 128254.
3. He, H.-Z.; Li, K.; Yu, K.-K.; Lu, P,-L.; Feng, M.-L. Chen, S.-Y.*; Yu, X.-Q. *,Additive- and column-free synthesis of rigid biscoumarins as fluorescent dyes for G-quadruplex sensing via disaggregation-induced emission, Chem. Commun., 2020,56, 6870.
4. Feng, M.-L.; L, S.-Q.; He, H.-Z.; Xi, L.-Y.; Chen, S.-Y.*; Yu, X.-Q. *, Electrochemically initiated intermolecular C–N formation/cyclization of ketones with 2-aminopyridines: an efficient method for the synthesis of imidazo[1,2-a]pyridines, Green Chem., 2019, 21,1619.
5. Wang, S.; Chen, S.-Y.*; Yu, X.-Q.*, C-H functionalization by high-valent Cp*Co(III) catalysis. Chem. Commun. 2017, 53, 3165-3180.
6. Feng, M.-L.; Xi, L.-Y.; Chen, S.-Y.*; Yu, X.-Q.*, Electrooxidative Metal-Free Dehydrogenative alpha-Sulfonylation of 1H-Indole with Sodium Sulfinates. Eur, J. Org. Chem. 2017, 2746-2750.
7. Zhang, R.-Y.; Xi, L.-Y.; Shi, L.; Zhang, X.-Z.; Chen, S.-Y.*; Yu, X.-Q.*, Metal-Free Oxidative Radical Alkynylation/Ring Expansion Rearrangement of AlkenylCyclobutanols with Ethynylbenziodoxolones. Org. Lett. 2016, 18, 4024-4027.
8. Wang, S.; Hou, J.-T.; Feng, M.-L.; Zhang, X.-Z.; Chen, S.-Y.*; Yu, X.-Q.*, Cobalt(III)-catalyzed alkenylation of arenes and 6-arylpurines with terminal alkynes: efficient access to functional dyes. Chem.Commun. 2016, 52, 2709-2712.
9. Chen, S.-Y.; Liu, W.; Wu, X.; Ying, J.; Yu, X.-Q*; Pu, L.*, A Lewis acid activated reaction of Zn with EtI to promote highly enantioselective alkyne additions to aldehydes. Chem. Commun. 2015, 51, 358-361.
10. Xi, L.-Y.; Zhang, R.-Y.; Liang, S.; Chen, S.-Y.*; Yu, X.-Q.*, Copper-Catalyzed Aerobic Synthesis of 2-Arylpyridines from Acetophenones and 1,3-Diaminopropane. Org. Lett. 2014, 16, 5269-5271.
11. Wang, S.; Guo, R.; Wang, G.; Chen, S.-Y.*; Yu, X.-Q.*, Copper-catalyzed phosphorylation of sp(2) C-H bonds. Chem. Commun. 2014, 50, 12718-12721.
12. Wang, G.; Yu, Q.-Y.; Chen, S.-Y.*; Yu, X.-Q.*, Et4NI-catalyzed amidationof aldehydes and alcohols with ammonium salts. Org. Biomol. Chem. 2014, 12, 414-417.
13. Liang, S.; Zhang, R.-Y.; Xi, L.-Y.; Chen, S.-Y.*; Yu, X.-Q.*, Sulfonylationof Five-Membered Heterocycles via anSNAr Reaction. J. Org. Chem. 2013,78, 11874-11880.
14. Liang, S.; Zhang, R.-Y.; Wang, G.; Chen, S.-Y.*; Yu, X.-Q.*, Transition-Metal-Free Synthesis of (E)-Vinyl Sulfones from Vinyl Halides in Water. Eur. J. Org. Chem. 2013, 7050-7053.